Septic spondylitis is one of the major diseases that cause back pain and should not be missed. A wide range of organisms have been associated with septic spondylitis and includes Mycobacterium tuberculosis, Staphylococcus aureus, Escherichia coli, Pseudomonas, Streptococci, and Kelbsiella. Salmonella is rare causative organism of bacterial spondylitis. It is known to cause a number of characteristic clinical infections in humans from gastroenteritis, enteric fever, and bacteremia to the asymptomatic carrier state. Salmonella spondylitis is associated with only small cases of all osteomyelitis cases and the majority of cases are frequently associated with patients with immunocompromised states, such as malignancies, long-term corticosteroid use, and sickle cell anemia. Here, we report our case about salmonella spondylitis occurred in a healthy adult without a specific medical history. He was treated with injection therapy at other local hospitals for a sustained back pain on thoracic region and temporarily improved. But, on 5 days after the injection, his back was suddenly aggravated again and he admitted for proper evaluation and management. Thoracic MRI showed septic spondylitis and salmonella was identified from bone biopsy. After 2 months of antibiotic treatment, he was cured.